GAD1 Antibody
货号：
5305S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 5305S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | GAD1 Antibody detects endogenous levels of total GAD1 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | The enzyme glutamate decarboxylase (GAD) is responsible for the synthesis of the essential neurotransmitter gamma-aminobutyric acid (GABA) from L-glutamic acid (1). GAD1 (GAD67) and GAD2 (GAD65) are expressed in nervous and endocrine systems (2) and are thought to be involved in synaptic transmission (3) and insulin secretion (4), respectively. Autoantibodies against GAD2 may serve as markers for type I diabetes (5). Many individuals suffering from an adult onset disorder known as Stiff Person Syndrome (SPS) also express autoantibodies to GAD2 (6).Mutations in the GAD1 gene can cause autosomal recessive spastic cerebral palsy, possibly attributable to altered glutamate/GABA ratios (7). |
| 存放说明 | -20C |
| 计算分子量 | 67 |
参考图片Western blot analysis of extracts from mouse and rat brain using GAD1 Antibody. Western blot分析小鼠和大鼠大脑提取物，使用的抗体是GAD1 Antibody 兔多抗。 |
