FYVE-CENT Antibody
货号:
8532S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 8532S |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | FYVE-CENT Antibody recognizes endogenous levels of total FYVE-CENT protein. |
使用方法 | WB(1:1000) IP (1:50) |
性能供应商 | CST |
背景 | FYVE-CENT (ZFYVE26) contains an FYVE zinc finger domain characterized by conserved R(R/RK) and HHCRxCG motifs (1). Phosphatidylinositol 3 phosphate binds to FYVE-CENT via the FYVE domain and this binding is crucial in phosphoinositide (PtdIns3P)-regulated cytokinesis (1-3). Research evidence suggests that during cytokinesis, FYVE-CENT directly interacts with TTC19 and is recruited to the midbody by the kinesin protein KIF13A (4). FYVE-CENT may also be involved in the tumor suppressor function of Beclin-1 (5). Researchers have linked the defects in FYVE-CENT to hereditary spastic paraplegia, a condition characterized by deterioration of the corpus callosum of the brain (6). |
存放说明 | -20C |
计算分子量 | 285 |
参考图片Western blot analysis of extracts from various cell lines using FYVE-CENT Antibody.使用FYVE-CENT抗体对多种细胞提取物进行western blot分析。 |