| 货号 | 3143S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IF-IC |
| 目标/特异性 | FoxA2/HNF3β Antibody detects endogenous levels of total FoxA2/HNF3β protein. |
| 使用方法 | WB(1:1000) IP (1:50) IF-IC (1:400) |
| 供应商 | CST |
| 背景 | Forkhead box protein A2 (FoxA2, also known as hepatocyte nuclear factor 3β or HNF3β) is a transcription factor that plays an important role in hepatocyte function (1). FoxA2/HNF3β is required for the activation of hepatic gluconeogenic gene expression during fasting (1). Together with the PGC-1β coactivator, FoxA2/HNF3β stimulates the expression of genes involved in fatty acid β-oxidation and therefore increases fatty acid metabolism (2). FoxA2/HNF3β, along with PGC-1β, also activates the expression of microsomal triacylglycerol transfer protein (MTP) and promotes VLDL secretion (2). In addition to its roles in metabolic syndromes, FoxA2/HNF3β is essential for development of the endoderm and midline structures in mouse embryos (3-5). |
| 存放说明 | -20C |
| 计算分子量 | 50 |
Western blot analysis of extracts from HepG2 cells using FoxA2/HNF3β Antibody. 对HepG2细胞抽提液使用FoxA2/HNF3β抗体进行Western blot分析。 | |
Confocal immunofluorescent analysis of HepG2 cells using FoxA2/HNF3β Antibody (green). Actin filaments have been labeled with DY-554 phalloidin (red). 对HepG2细胞使用FoxA2/HNF3β抗体（绿色）进行共聚焦免疫荧光分析。肌动蛋白用DY-554 phalloidin（红色）标记。 |
