货号 | 5258S |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | Fetuin A (F180) Antibody detects endogenous levels of total fetuin A protein. |
使用方法 | WB(1:1000) IP (1:50) |
供应商 | CST |
背景 | Fetuin A is produced by liver and secreted to plasma, and selectively concentrated in bone matrix. It is synthesized as a precursor and processed to generate 2 chains that are held together by a disulfide bond. It is a systemically acting calcification inhibitor (1). Reduced level of fetuin A in serum is associated with increased cardiovascular mortality in dialysis patients (2,3). Fetuin A can inhibit insulin-induced tyrosine phosphorylation of the insulin receptor tyrosine kinase and insulin receptor substrate-1 (4). Fetuin A deficient mice show high insulin sensitivity and high levels of serum fetuin A are associated with insulin resistance in humans (5,6). |
存放说明 | -20C |
计算分子量 | 45-50 |
Western blot analysis of human serum using Fetuin A (F180) Antibody. Human serum (0.1 μl) was analyzed. western blot检测人血清(0.1 μl),所用抗体为Fetuin A (F180) Antibody |