| 货号 | 3285S |
| 反应种属 | Human/Mouse/Rat/Monkey/Bovine/Pig |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IHC-P |
| 目标/特异性 | FAK Antibody detects endogenous levels of FAK protein. This antibody does not cross-react with other proteins. |
| 使用方法 | WB(1:1000) IP (1:50) IHC-P (1:800) |
| 供应商 | CST |
| 背景 | Focal adhesion kinase (FAK) is a widely expressed cytoplasmic protein tyrosine kinase involved in integrin-mediated signal transduction. It plays an important role in the control of several biological processes, including cell spreading, migration, and survival (1). Activation of FAK by integrin clustering leads to autophosphorylation at Tyr397, which is a binding site for the Src family kinases PI3K and PLCγ (2-5). Recruitment of Src family kinases results in the phosphorylation of Tyr407, Tyr576, and Tyr577 in the catalytic domain, and Tyr871 and Tyr925 in the carboxy-terminal region of FAK (6,7). |
| 存放说明 | -20C |
| 计算分子量 | 125 |
Western blot analysis of extracts from various cell lines, using FAK Antibody.使用FAK抗体对多种细胞提取物进行western blot分析。 | |
Immunohistochemical analysis of paraffin-embedded human lung carcinoma, using FAK Antibody in thre presence of control peptide (left) or antigen-specific peptide (right).在对照肽（左）或抗原特异性多肽（右）存在的条件下使用FAk抗体对石蜡包埋的人肺癌组织进行免疫组化分析。 | |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma, using FAK Antibody.使用FAK抗体对石蜡包埋的人乳腺癌组织进行免疫组化分析。 |
