FABP4 Antibody
货号：
2120S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2120S |
| 反应种属 | Mouse |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | FABP4 Antibody detects endogenous levels of total FABP4 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Fatty acid binding proteins (FABPs) bind to fatty acids and other lipids to function as cytoplasmic lipid chaperones (1). They participate in the transport of fatty acids and other lipids to various cellular pathways (2). The predominant fatty acid binding protein found in adipocytes is FABP4, also called adipocyte fatty acid binding protein or aP2. FABP4 is also expressed in macrophages (3). FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes (4). Mice deficient in both FABP4 and ApoE show protection against atherosclerosis when compared with mice deficient only in ApoE (3). Mice carrying a FABP4 genetic variant exhibit both reduced FABP4 expression and a reduced potential for developing type 2 diabetes and coronary heart disease. A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders (1). |
| 存放说明 | -20C |
| 计算分子量 | 15 |
参考图片Western blot analysis of extracts from NIH/3T3 and 3T3-L1 cells using FABP4 Antibody. 对NIH/3T3和3T3-L1细胞抽提液使用FABP4 Antibody进行Western blot分析。 |
