ERp44 Antibody
货号:
2886S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 2886S |
反应种属 | Human/Mouse/Rat/Monkey |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | ERp44 Antibody detects endogenous levels of total ERp44 protein. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | Secretory proteins translocate into the endoplasmic reticulum (ER) after their synthesis where they are post-translationally modified and properly folded. To reach their native conformation, many secretory proteins require the formation of intra- or inter-molecular disulfide bonds (1). This process is called oxidative protein folding. Disulfide isomerase (PDI) has two thioredoxin homology domains and catalyzes the formation and isomerization of these disulfide bonds (2). Other ER resident proteins that possess the thioredoxin homology domains, including endoplasmic reticulum resident protein 44 (ERp44), constitute the PDI family (2). ERp44 is induced upon ER stress and is linked to Ero1-Lα and Ero1-Lβ through mixed disulfide bonds (3). ERp44 was shown to mediate the ER localization of Ero1-Lα (4). |
存放说明 | -20C |
计算分子量 | 44 |
参考图片Western blot analysis of extracts from various cell types using ERp44 Antibody. 对多个细胞系使用ERp44 Antibody进行Western blot分析。 |