Erlin-1 Antibody
货号：
2958S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2958S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Erlin-1 Antibody detects endogenous levels of total human erlin-1 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Erlin-1 and erlin-2 (SPFH1 and SPFH2) are SPFH domain-containing proteins that belong to the prohibitin family (1,2). The N-termal domain of erlin proteins contains ER-targeting sequences responsible for their translocation to the endoplasmic reticulum (ER) (3). In the ER, erlin-1 and erlin-2 specifically associate with the detergent resistant lipid raft microdomain of the membrane (3). Erlin-1 may be involved in dentritic cell activation (4) and erlin-2 has been shown to regulate the ER-associated degradation (ERAD) pathway by interacting with endogenous substrates and resulting in their polyubiquitination and degradation (5). |
| 存放说明 | -20C |
| 计算分子量 | 43 |
参考图片Western blot analysis of extracts from human U937 and ovcar8 cell lines using Erlin-1 Antibody. 使用Erlin-1 Antibody，免疫印迹（Western Blot）分析人源U937和ovcar8细胞中Erlin-1蛋白水平。 |
