ENPP1 Antibody (Human Specific)
货号：
2070S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2070S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | ENPP1 Antibody (Human Specific) detects endogenous levels of total ENPP1 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Ectonucleotide pyrophosphatase-phosphodiesterase 1 (ENPP1) is a single-pass, type II transmembrane protein primarily involved in ATP hydrolysis at the plasma membrane. Targeting of ENPP1 to the basolateral cell surface relies on the presence of a carboxy-terminal di-leucine-based signal (1). ENPP1 plays important roles in bone mineralization and soft tissue calcification (2-5). Mutations in the corresponding ENPP1 gene cause generalized arterial calcification in infancy (GACI) and idiopathic infantile arterial calcification (IIAC) (6,7). ENPP1 inhibits insulin receptor function and overexpression of this enzyme causes insulin resistance and glucose intolerance in mice (8,9). Genetic variants of ENPP1 have been associated with obesity and type 2 diabetes (10-12). |
| 存放说明 | -20C |
| 计算分子量 | 140 |
参考图片Western blot analysis of extracts from HepG2 and MDA-MB-231 cells using ENPP1 Antibody (Human Specific). 对HepG2和MDA-MB-231细胞裂解液使用ENPP1 Antibody（人特异性）进行Western blot分析。 |
