Emerin (L12) Antibody
货号：
2659S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2659S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | Emerin (L12) Antibody detects endogenous levels of total Emerin protein. |
| 使用方法 | WB(1:1000)
IP (1:50) |
性能| 供应商 | CST |
| 背景 | Emerin is a broadly expressed integral protein of the nuclear inner membrane (1). It contains a LEM domain and binds to several nuclear proteins, such as BAF (barrier-to-autointegration factor) and A- and B-type lamins, which are important in nuclear functions (2-5). Emerin may regulate gene expression through binding to other transcriptional regulators (6,7). Emerin binds to β-catenin and inhibits its nuclear accumulation (8). Recent studies demonstrate that Emerin is required for HIV-1 infectivity (9). Mutations in Emerin are a major cause of Emery-Dreifuss muscular dystrophy (EDMD), a disorder characterized by progressive skeletal muscle weakening (10). |
| 存放说明 | -20C |
| 计算分子量 | 30 |
参考图片Western blot analysis of extracts from various cell types using Emerin (L12) Antibody.使用Emerin (L12) Antibody，免疫印迹（Western Blot）分析不同细胞中Emerin(L12)蛋白水平。 |
