E2A Antibody
货号：
4865S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 4865S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | E2A Antibody detects endogenous levels of total E2A protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | E2A is a member of the E-protein family of transcription factors, a subclass of basic helix-loop-helix (bHLH) proteins that bind specifically to E-box consensus sequences (1,2). Alternative splicing generates two E2A isoforms (E47 and E12) that are actively involved in B-cell lineage commitment, B-lymphocyte maturation, IgK V-J rearrangement, peripheral B-cell development, and tumor suppression (3). E2A acts in cis during G1 to promote immunoglobulin gene diversification (4). Chromosomal translocations involving the E2A gene result in the expression of multiple fusion proteins and are associated with many cases of pediatric acute lymphoblastic leukemia (5). |
| 存放说明 | -20C |
| 计算分子量 | 75 |
参考图片Western blot analysis of extracts from various cell lines using E2A Antibody.Western免疫印迹。用E2A Antibody研究各种细胞系的细胞提取液。 |
