货号 | 2342S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | Dynamin I/II Antibody detects endogenous levels of total dynamin protein. The antibody does not recognize the related dynamin-like protein DLP. |
使用方法 | WB(1:1000) IP (1:30) |
供应商 | CST |
背景 | Dynamin is a family of large GTPases that has been implicated in the formation of vesicles of both the endocytotic and secretory processes (1). Dynamin plays an important role in the internalization of cell surface receptors, a process that attenuates the response to extracellular signals. It has been illustrated that dynamin interacts with signaling proteins such as Src, PLCγ, PKC and G-proteins. PKC and Src phosphorylate dynamin, and its phosphorylation may regulate the endocytosis of cell surface receptors (2,3). |
存放说明 | -20C |
计算分子量 | 100 |
Western blot analysis of extracts from NIH/3T3, PC12 and HEK293 cells using Dynamin I/II Antibody. 对NIH/3T3, PC12和HEK293细胞提取物使用Dynamin I/II Antibody进行Western blot分析。 | |
Dynamin was immunoprecipitated from PC12 and HEK293 cells followed by western blot analysis using Dynamin I/II Antibody. 在Western blot分析后,使用Dynamin I/II Antibody对PC12和HEK293细胞进行Dynamin免疫共沉淀。 |