Dopamine β-Hydroxylase (DBH) Antibody
货号：
8586S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 8586S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Dopamine β-Hydroxylase (DBH) Antibody recognizes endogenous levels of total DBH protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Dopamine β-Hydroxylase (DBH) is an enzyme of the copper type II ascorbate-dependent mono-oxygenase family. This enzyme forms homotetramers composed of two noncovalently bound disulfide-linked dimers and is found as both membrane-associated and soluble forms (1-3). The soluble form is present in the lumen of secretory granules (4) and is released from cells by exocytosis (5). DBH converts dopamine to noradrenaline (6). Deficiency in this enzyme causes a rare disease characterized by a complete absence of noradrenaline and adrenaline in plasma together with increased plasma dopamine levels (7). Orthostatic hypotension, the main symptom of DBH deficiency, can be alleviated by administration of dihydroxyphenylserine, a synthetic precursor of noradrenaline (8). |
| 存放说明 | -20C |
| 计算分子量 | 75-80 |
参考图片Western blot analysis of extracts from SH-SY5Y cells, untreated (-) or treated with TPA (200 nM, 24 hr) #4174 (+), and 293 cells, using Dopamine β-Hydroxylase (DBH) Antibody. Western blot分析SH-SY5Y细胞未处理，或200nM TPA #4174 (+) 处理24小时，和293细胞提取物，使用的抗体是Dopamine β-Hydroxylase (DBH) Antibody 兔多抗。 |
