| 货号 | 5556S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | DLST Antibody detects endogenous levels of total DLST protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | α-ketoglutarate dehydrogenase complex is a rate-regulating enzyme in the Krebs Cycle in mitochondria (1). Dihydrolipoamide succinyltransferase (DLST) is a key subunit in this complex (2). Mutations in the DLST gene may be responsible for the familial Alzheimer disease (1). Reduction of DLST increases the generation of reactive oxygen species production suggesting its role in oxidative stress (2). Deficiency of DLST in mice was suggested to cause increased oxidative stress in mitochondria and is involved in the pathogenesis of Alzheimer disease (2). |
| 存放说明 | -20C |
| 计算分子量 | 50 |
Western blot analysis of extracts from various cell lines using DLST Antibody. Wetern blot检测多种细胞系提取物，所用抗体为DLST Antibody。 |
