DCBLD2 Antibody
货号：
4804S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 4804S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | DCBLD2 Antibody detects endogenous levels of total DCBLD2 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | DCBLD2 (discoidin, CUB and LCCL domain-containing 2; also known as ESDN and CLCP1) is a type I transmembrane protein that is structurally similar to neuropilin family proteins and contains the longest known amino-terminal secretory signal sequence among eukaryotic proteins (1). Highly expressed in nerve bundles, vascular smooth muscle cells and upregulated following vascular injury, DCBLD2 may be involved in a wide range of functions in the nervous and vascular systems (1,2). Studies have found DCBLD2 to be upregulated in several types of lung cancer with an especially high frequency in metastatic lesions and lymph node metastasis, implicating a role in the process of tumor progression and metastatic capability (3). DCBLD2 has also been identified as part of a complex EGF phosphotyrosine signaling network, serving as a novel tyrosine phosphorylation target of EGF signaling in human cancer cells (4). |
| 存放说明 | -20C |
| 计算分子量 | 120 |
参考图片Western blot analysis of extracts from HL-60, MKN-45 and HCC827 cells using DCBLD2 Antibody. Western blot分析HL-60、MKN-45和HCC827细胞提取物，使用的抗体是DCBLD2 Antibody 兔多抗。 |
