Cyclophilin A Antibody
货号：
2175S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2175S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Cyclophilin A Antibody detects endogenous levels of total Cyclophilin A protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Cyclophilins are a highly conserved family of peptidylprolyl cis-trans-isomerases (PPIA) that are targets of the immunosuppressant drug cyclosporin A (CsA) (1,2). The complex of cyclophilin and CsA can bind to and inhibit calcineurin which leads to inhibition of the transcription factor NFAT and decreased production of cytokines (3,4). As isomerases, cyclophilins have been proposed to aid in protein folding. Cyclophilin A can bind to the p55 Gag protein of HIV and appears necessary for HIV infection (5,6). There is also some evidence that cyclophilins have nuclease activity and play a role in apoptosis (7). |
| 存放说明 | -20C |
| 计算分子量 | 18 |
参考图片Western blot analysis of extracts from HeLa (human), NIH/3T3 (mouse) and KNRK (rat) cell lines, using Cyclophilin A Antibody.Western免疫印迹。用Cyclophilin A Antibody研究HeLa (人源), NIH/3T3 (小鼠源) 和 KNRK (大鼠源)细胞的细胞提取液。 |
