CIITA Antibody
货号：
3793S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 3793S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | CIITA Antibody detects transfected levels of total CIITA protein. |
| 使用方法 | WB(1:1000)
IP (1:50) |
性能| 供应商 | CST |
| 背景 | MHC class II (MHC-II) proteins play critical roles in cellular immune responses and their expression is mainly regulated by the non-DNA binding transcription factor CIITA (MHC class II transactivator) (1,2). CIITA expression is upregulated by IFN-γ and it in turn enchances MHC-II expression and represses collagen expression (3,4). CIITA has a limited number of transcriptional targets, most of which are involved in MHC-mediated antigen presentation (5). Mutations in the CIITA are associated with the hereditary immunodeficiency disease Bare Lymphocyte Syndrome (BLS) which is characterized by a nearly complete absence of MHC-II expression (also referred to as MHC-II deficiency) (6,7). |
| 存放说明 | -20C |
| 计算分子量 | 140 |
参考图片Western blot analysis of extracts from COS cells, mock transfected or transfected with human CIITA, using CIITA Antibody.Western免疫印迹。用CIITA Antibody研究对照转染和转染了人源CIITA COS细胞的细胞提取液。 |
