Centrin-2 Antibody
货号：
2091S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2091S |
| 反应种属 | Human/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Centrins are small conserved microtubule nucleating proteins localized to centrosomes, also known as microtubule organizing centers (MTOC), in eukaryotic cells. Centrin-1 is associated with cells that have cilia and flagella, whereas centrin-2 and -3 are ubiquitously expressed and important in centrosome duplication during cell division, as well as the structure and function of the MTOC (1-3). Human centrin-2 has also been shown to localize to nuclear pores and to have a role in regulation of mRNA export (4). The yeast ortholog of centrin-2, CDC31, plays a part in control of protein degradation and sensitivity to DNA damage (5).在真核细胞中，Centrins蛋白是小的保守微管成核蛋白质，其定位于中心体，又称为微管组织中心（microtubule organizing centre,MTOC）。Centrin-1 蛋白与含有纤毛和鞭毛的细胞有联系，然而 centrin-2 和-3普遍表达，并且在细胞分裂时中心体复制有着重要作用，和MTOC的结构和功能一样(1-3)。研究已经显示人源centrin-2蛋白定位于核孔，并且在mRNA输出的调节中有作用 (4)。centrin-2蛋白的酵母同系物CDC31蛋白参与控制蛋白质降解和敏感DNA损伤 (5)。 |
| 存放说明 | -20C |
| 计算分子量 | 20 |
参考图片Western blot analysis of extracts from various cell lines using Centrin-2 Antibody.使用Centrin-2 Antibody，免疫印迹（Western Blot）分析不同细胞系Centrin-2蛋白水平。 |
