CDX2 Antibody
货号:
3977S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 3977S |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | Cdx2 Antibody detects endogenous levels of total Cdx2 protein. |
使用方法 | WB(1:1000) IP (1:100) |
性能供应商 | CST |
背景 | Cdx2, a homeobox domain-containing transcription factor, is a master regulator of the trophoectoderm, the layer that gives rise to extra-embryonic tissues in mammalian development (1). Cdx2 is also involved in intestinal development (2), and gain of expression or loss of expression has been associated with various human malignancies such as Barret Esophagus (3) and colorectal cancer (4,5). Mouse embryonic stem cells deficient in Cdx2 display limited hematopoietic progenitor development and altered Hox gene expression (6), pointing to a role for Cdx2 in Hox gene regulation. Cdx2 is also implicated in the aberrant expression of Hox genes in human AML cell lines (7). |
存放说明 | -20C |
计算分子量 | 38 |
参考图片Western blot analysis of extracts from DLD-1 and MCF7 (CDX2-null) cells using CDX2 Antibody. |