| 货号 | 5478S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IF-IC |
| 使用方法 | WB(1:1000) IP (1:100) IF-IC (1:50) |
| 供应商 | CST |
| 背景 | CD2AP is a scaffolding protein that is thought to link membrane proteins to the cytoskeleton (1-3). It plays a role in formation of tight junctions in specialized cell types such as the slit diaphragm in the kidney glomerulus (4). CD2AP is also involved in the immunological synapse between CD2 expressing T cells and antigen presenting cells (5). It has been shown that interaction between CD2AP and other cytoskeletal proteins may regulate the endocytosis of EGFR (3).CD2AP蛋白是一个支架蛋白，其被认为膜蛋白联系到细胞骨架(1-3)。该蛋白在专门的细胞类型的紧密连接的形成中扮演重要角色，例如在肾小球的裂孔隔膜(4)。CD2AP蛋白也涉及T细胞表达的CD2与抗原呈递细胞之间的免疫突触(5)。研究证明 CD2AP蛋白和其它细胞支架蛋白之间的相互作用可能调节EGFR蛋白的内吞作用 (3)。 |
| 存放说明 | -20C |
| 计算分子量 | 80 |
Confocal immunofluorescent analysis of A-431 cells using CD2AP (A599) Antibody (green). Actin filaments were labeled with DY-554 phalloidin (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).使用CD2AP (A599) Antibody (绿色)标记，共聚焦免疫荧光分析A-431细胞。DY-554 phalloidin标记微丝（红色）。蓝色= DRAQ5® #4084（DNA荧光染料）。 | |
Western blot analysis of extracts from various cell lines using CD2AP (A599) Antibody.使用CD2AP (A599) Antibody，免疫印迹（Western Blot）分析不同细胞系CD2AP(A599)蛋白水平。 |
