CCN3 Antibody
货号：
8767S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 8767S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | CCN3 Antibody recognizes endogenous levels of total CCN3 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | CCN3, also named NOV (Nephroblastoma overexressed), belongs to the CCN (Cyr61, Ctgf, NOV) family of proteins. It is a cystine-rich secretory protein that associates with components of the extracellular matrix. Like other CCN family members, CCN3 is capable of mediating diverse biological functions through its four distinct domains, which enable binding to numerous protein partners (1-5).
CCN3 modulates bone turnover through various mechanisms and is implicated in the progression of primary bone cancers such as osteosarcoma and chondrosarcoma (6-8). Research has shown that CCN3 is also involved in the bone metastasis of melanoma, breast cancer, and prostate cancers (9-11). Recently, CCN3 was reported to play an important role in stem cell renewal (12). CCN3 is normally expressed in both embryonic and adult tissues (13,14). The activity of CCN3 is influenced by post translational modifications and proteolytic cleavage (15,16). |
| 存放说明 | -20C |
| 计算分子量 | 43 |
参考图片Western blot analysis of extracts from A172 and ACHN cells using CCN3 Antibody. Western blot分析A172和ACHN细胞提取物，使用的抗体是CCN3 Antibody。 |
