Caspase-8 Antibody (Mouse Specific)
货号:
4927S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 4927S |
反应种属 | Mouse |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | Caspase-8 Antibody (mouse specific) detects endogenous levels of mouse caspase-8 protein. This antibody will detect the large 18kDa subunit of active caspase-8. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | Apoptosis induced through the CD95 receptor (Fas/APO-1) and tumor necrosis factor receptor 1 (TNFR1) activates caspase-8 and leads to the release of the caspase-8 active fragments, p18 and p10 (1-3). Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1, -3, -6, and -7. Caspase-3 ultimately elicits the morphological hallmarks of apoptosis, including DNA fragmentation and cell shrinkage. |
存放说明 | -20C |
计算分子量 | 45, 57 |
参考图片Western blot analysis of extracts from BaF3, Raw264.7 and C2C12 cell lines, using Caspase-8 Antibody (mouse specific). Western blot 检测BaF3、Raw264.7和C2C12细胞系提取物,使用抗体为Caspase-8 Antibody (mouse specific)。 |