Caspase-6 Antibody
货号：
9762S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 9762S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes (1,2). Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated (3). The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis (4,5). One of the major targets for caspase-6 is the membrane associated protein lamin A (6). The cleavage of this protein causes cell membrane malfunction, membrane blebbing and eventual cell death. |
| 存放说明 | -20C |
| 计算分子量 | 15, 35 |
参考图片Western blot analysis of extracts from NIH/3T3 cells, untreated or staurosporine-treated (1 µM) and Jurkat cells, untreated or etoposide-treated (25 µM), using Caspase-6 Antibody. 采用抗体Caspase-6 Antibody，对未处理或 staurosporine （星胞菌素 ）(1 µM)处理 的NIH/3T3 细胞，以及未处理或 etoposide (25 µM)处理的 Jurkat 细胞进行Western blot分析。 |
