Calreticulin Antibody
货号：
2891S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 2891S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Calreticulin Antibody detects endogenous levels of total calreticulin protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Calcium is a universal signaling molecule involved in many cellular functions such as cell motility, metabolism, protein modification, protein folding, and apoptosis. Calcium is stored in the endoplasmic reticulum (ER), where it is buffered by calcium binding chaperones such as calnexin and calreticulin, and is released via the IP3 Receptor channel (1). Calreticulin also functions as an ER chaperone that ensures proper folding and quality control of newly synthesized glycoproteins. As such, calreticulin presumably does not alter protein folding but regulates proper timing for efficient folding and subunit assembly. Furthermore, calreticulin retains proteins in non-native conformation within the ER and targets them for degradation (2,3). |
| 存放说明 | -20C |
| 计算分子量 | 55 |
参考图片Western blot analysis of extracts from HeLa and C6 cells using Calreticulin Antibody. 对HeLa和C6细胞裂解物使用Calreticulin抗体进行Western blot分析。 |
