C1QBP Antibody
货号:
5734S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 5734S |
反应种属 | Human/Mouse/Rat/Monkey |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | C1QBP Antibody recognizes endogenous levels of total C1QBP protein. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | C1QBP, also referred to as p32, p33, gC1q receptor (gc1qR), and hyaluronic acid binding protein 1 (HABP1), was originally identified via its binding interactions with Splicing Factor (SF-2) (1). Multiple, diverse binding partners of C1QBP were subsequently identified, including the globular heads of complement component c1q, hyaluronic acid, selected protein kinases (2), the tumor suppressor ARF (3, 4, 5), and multiple antigens of bacterial and viral origin (6). C1QBP is overexpressed in a number of cancer cell types (7), and has been implicated in the Warburg effect, whereby cancer cells shift their metabolism from oxidative phosphorylation to glycolysis (7). C1QBP has also been shown to inhibit the Mitochondrial Permeability Transition (MPT) pore, possibly serving a protective function against damage from oxidative stress (8). |
存放说明 | -20C |
计算分子量 | 28 |
参考图片Western blot analysis of extracts from various cell lines using C1QBP Antibody. Wetern blot检测多种细胞系提取物,所用抗体为C1QBP Antibody。 |