C/EBPbeta Antibody
货号:
3082S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 3082S |
反应种属 | Rat |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | C/EBPbeta Antibody detects endogenous levels of rat C/EBPbeta protein. It does not cross-react with other C/EBP family members such as C/EBPalpha, -delta, -gamma, -epsilon or -zeta. It also does not recognize the p20 LIP rat C/EBPbeta isoform. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | CCAAT/enhancer-binding proteins (C/EBPs) are a family of transcription factors critical for cellular differentiation, terminal functions and inflammatory response (1). Six members of the family have been characterized (C/EBPα, -β, -γ, -δ, -ε and -ζ) and are distributed in a variety of tissues (1). There are two forms of C/EBPβ, the 38 kDa liver activating protein (LAP) and the 20 kDa liver inhibitory protein (LIP) which may be products of alternative translation. The 38 kDa LAP protein is a transcriptional activator while LIP may act as an inhibitor of C/EBPβ transcriptional activity (2). Phosphorylation of C/EBPβ at distinct sites stimulates its transcriptional activity (3-5). Phosphorylation at serine 105 of rat C/EBPβ, a unique site only present in the rat sequence, seems essential for rat C/EBPβ activation (6). |
存放说明 | -20C |
计算分子量 | 38, 41 |
参考图片Western blot analysis of extracts from untreated or serum treated PC12 cells, using C/EBPbeta Antibody. 对PC12细胞抽提液,未处理或血清处理,使用C/EBPbeta抗体进行Western blot分析。 |