C/EBPalpha (p42) Antibody
货号:
2843S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 2843S |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | C/EBPalpha (p42) Antibody detects endogenous levels of total p42 C/EBPalpha protein but not p30 C/EBPalpha. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | CCAAT/enhancer-binding proteins (C/EBPs) are a family of transcription factors that are critical for cellular differentiation, terminal function and inflammatory response (1). Six members of the family have been characterized (C/EBPα, β, δ, γ, ε and ζ) and are distributed in a variety of tissues (1). Translation from alternative start codons results in two isoforms of C/EBPα (p42 and p30), which are both strong transcriptional activators (2). It has been reported that insulin and insulin-like growth factor-1 stimulate the dephosphorylation of C/EBPα, which may play a key role in insulin induced repression of GLUT4 transcription (3). Phosphorylation of C/EBPα at Thr222, Thr226 and Ser230 by GSK3 seems to be required for adipogenesis (4). |
存放说明 | -20C |
计算分子量 | 45 |
参考图片Western blot analysis of extracts from U937 cells, using C/EBPalpha (p42) Antibody. 对U937细胞抽提液使用C/EBPalpha (p42) Antibody进行Western blot分析。 |