BSP II Antibody
货号：
5468S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 5468S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | The BSP II Antibody detects endogenous levels of total BSP II protein. |
| 使用方法 | WB(1:1000)
IP (1:50) |
性能| 供应商 | CST |
| 背景 | Bone sialoprotein II (BSP II) exists as a secreted protein in extracellular matrix of the skeleton (1-2). BSP II is part of the small integrin binding ligand N-linked glycoprotein (SIBLING) family and its role is crucial for cell to matrix adhesion as well as between two active protein complexes (3). Flexible binding capacity of BSP II also allows it to rapidly associate with various proteins, calcium, and mineralized phases of developing bone (3-5). BSP II plays a central role in the initiation of hydroxyapatite microcalcification of breast cancer cells that contributes to the pathogenesis of bone metastasis (4,6,7). Recent evidence suggests that the downregulation of BSP II may lead to the reduced formation of metastatic lesions and bone metastasis in a human breast cancer model (5). |
| 存放说明 | -20C |
| 计算分子量 | 82 |
参考图片Western blot analysis of extracts from MDA-MB-435, U-2 OS, and Saos-2 cells using BSP II Antibody.使用BSP II抗体对MDA-MB-435, U-2 OS和Saos-2细胞提取物进行western blot分析。 |
