BMP7 Antibody
货号：
4693S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 4693S |
| 反应种属 | Mouse |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | BMP7 Antibody detects transfected levels of total mouse BMP7 protein. It only recognizes the BMP7 precursor protein (49 kDa), not the mature secreted from (16 kDa). |
| 使用方法 | WB(1:1000)
IP (1:50) |
性能| 供应商 | CST |
| 背景 | Bone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation (1,2). BMPs belongs to the TGF-β superfamily, playing many diverse functions during development (3). BMPs are synthesized as precursor proteins and then processed by cleavage to release the c-terminal mature BMP. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5 and 8), resulting the translocation of Smad into the nucleus. BMP was also reported to activate MAPK pathways in some systems (3,4). |
| 存放说明 | -20C |
| 计算分子量 | 49 |
参考图片Western blot analysis of extracts from COS cells, mock transfected or transfected with mouse BMP7, using BMP7 Antibody.小鼠BMP7转染或未转染的COS细胞，获得提取物进行Western blot实验，使用BMP7抗体检测。 |
