BiP Antibody
货号：
3183S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 3183S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | BiP Antibody detects endogenous levels of total BiP protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Secretory and transmembrane proteins are synthesized on polysomes and translocated into the endoplasmic reticulum (ER). Inside the ER, these proteins are often modified by disulfide bond formation, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including BiP. BiP was identified as an immunoglobulin heavy chain binding protein in pre-B cells (1,2). It was also found to be induced at the protein level by glucose starvation (3). When protein folding is disturbed inside ER, BiP synthesis is increased. Subsequently, BiP binds to misfolded proteins to prevent them from forming aggregates and assists in proper refolding (4). |
| 存放说明 | -20C |
| 计算分子量 | 78 |
参考图片Western blot analysis of extracts from several cell lines using BiP Antibody. 对多个细胞系使用BiP Antibody进行Western blot分析。 |
