| 货号 | 2774S |
| 反应种属 | Human/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IHC-P |
| 目标/特异性 | Bax Antibody (Human-Specific) detects endogenous levels of total Bax protein. Cross-reativity was not detected with other family members at physiological conditions. |
| 使用方法 | WB(1:1000) IP (1:50) IHC-P (1:100) |
| 供应商 | CST |
| 背景 | Bax is a key component for cellular induced apoptosis through mitochondrial stress (1). Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane (2). Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membranes permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis (3,4). |
| 存放说明 | -20C |
| 计算分子量 | 20 |
Western blot analysis of extracts from 293, HT-1080 and Raji cell lines using Bax Antibody #2772 (left) and Bax Antibody (Human Specific) #2774 (right). 用 Bax Antibody #2772 (左图) 和 Bax Antibody (Human Specific) #2774 (右图)，对293、HT-1080 和 Raji 细胞的细胞提取液进行Western免疫印迹。 | |
Immunohistochemical analysis of paraffin-embedded human lung carcinoma using Bax Antibody (Human Specific). 免疫组织化学染色分析石蜡包埋人肺癌组织。所用抗体为Bax Antibody (Human Specific)。 | |
Immunohistochemical analysis of paraffin-embedded human Non-Hodgkins lymphoma using Bax Antibody (Human Specific). 免疫组织化学染色分析石蜡包埋人非霍奇金淋巴癌组织。所用抗体为Bax Antibody (Human Specific)。 |
