| 货号 | 4043S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | BAP31 Antibody detects endogenous levels of total BAP31 protein. |
| 使用方法 | WB(1:1000) IP (1:25) |
| 供应商 | CST |
| 背景 | BAP31 (B-cell receptor-association protein 31) is a transmembrane protein associated with the endplasmic reticulum (ER) and ER-Golgi intermediates and has been implicated in protein trafficking and apoptosis (1,2). During apoptosis Bap31 is cleaved by caspase-8 at two carboxy-terminal sites which can then direct apoptotic signals between the ER and mitochondria (2-4). Association of BAP31 with the anti-apoptotic proteins Bcl-2 or Bcl-xL could function to regulate this ER-mitochondrial pathway (2,5). Several studies have shown that BAP31 can control the trafficking of select proteins between the ER and Golgi apparatus and can affect the transport of proteins to the cell surface (6-10). |
| 存放说明 | -20C |
| 计算分子量 | 28 |
Western blot analysis of extracts from COS cells, mock transfected or transfected with human BAP31, and from various cell types using BAP31 Antibody. Western免疫印迹。用BAP31 Antibody研究分别转染了对照或人源BAP31的 COS 细胞和各种类型细胞的细胞提取液。 |
