Bak Antibody
货号：
3814S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 3814S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Bak Antibody detects endogenous levels of Bak protein. No cross reactivity was detected with other Bcl-2 family members. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Bak is a proapoptotic member of the Bcl-2 family (1). This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway (2,3). Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase-9 pathway and eventually leads to cell death (4,5). |
| 存放说明 | -20C |
| 计算分子量 | 25 |
参考图片Western blot analysis of extracts from OVCAR8, HT29 and Jurkat cells using Bak Antibody. Western blot 免疫印迹。用Bak Antibody分析OVCAR8、HT29和Jurkat细胞的细胞提取液。 |
