ATP-Citrate Lyase Antibody
货号：
4332S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 4332S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | ATP-Citrate Lyase Antibody detects endogenous levels of total ATP-citrate lyase. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | ATP-citrate lyase (ACL) is a homotetramer that catalyzes the formation of acetyl-CoA and oxaloacetate (OAA) in the cytosol, which is the key step for the biosynthesis of fatty acids, cholestrol and acetylcholine, as well as for glucogenesis (1). Nutrients and hormones regulate the expression level and phosphorylation of ATP-citrate lyase (1,2). It is phosphorylated by GSK-3 on Thr446 and Ser450 (3). Ser455 of ATP-citrate lyase has been reported to be phosphorylated by PKA and Akt (4,5). Phosphorylation on Ser455 abolishes the homotropic allosteric regulation by citrate and enhances the catalytic activity of the enzyme (2). |
| 存放说明 | -20C |
| 计算分子量 | 125 |
参考图片Western blot analysis of extracts from HeLa, NIH/3T3, C6 and COS cells, using ATP-Citrate Lyase Antibody. Wetern blot检测HeLa, NIH/3T3, C6 和COS 提取物，所用抗体为ATP-Citrate Lyase Antibody |
