| 货号 | 2138S |
| 反应种属 | Mouse |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IHC-P/IF-IC |
| 目标/特异性 | ATGL Antibody detects endogenous levels of total ATGL protein. |
| 使用方法 | WB(1:1000) IP (1:100) IHC-P (1:800) IF-IC (1:400) |
| 供应商 | CST |
| 背景 | Triglycerides form an important energy store in many living organisms. Adipose tissue serves as the primary storage depot for triglycerides in mammals. Lipolytic enzymes mobilize triglycerides during periods of starvation to provide organisms with necessary energy. Hormone-sensitive lipase (HSL), the first identified lipolytic enzyme, hydrolyzes triglycerides in mammalian adipose tissues (1-3). Additional lipolytic enzymes, including adipose triglyceride lipase (ATGL), have also been discovered. The primary function of ATGL is to catalyze the hydrolysis of the first ester bond of lipid molecules. This enzyme may provide diglyceride substrates for HSL hydrolysis. ATGL is abundantly expressed in murine white and brown adipose tissue, and is highly substrate specific (4). ATGL was independently identified as desnutrin (5) and the TG-hydrolace inducible phospholipase-A2-ζ (6). |
| 存放说明 | -20C |
| 计算分子量 | 54 |
Immunohistochemical analysis of paraffin-embedded NIH/3T3-L1 cells undifferentiated (left) or differentiated (right), showing induced staining in adipocytes, using ATGL Antibody. 对NIH/3T3-L1细胞，未分化（左）或分化的（右），使用ATGL Antibody进行免疫组化分析，显示出诱导的脂肪细胞染色。 | |
Immunohistochemical analysis of paraffin-embedded mouse lung, showing specific staining of fat, using ATGL Antibody. 对石蜡包埋的小鼠肺使用ATGL Antibody进行免疫组化分析，显示脂肪特异的染色。 | |
Immunohistochemical analysis of paraffin-embedded mouse brown fat, using ATGL Antibody in the presence of control peptide (left) or antigen-specific peptide (right). 对石蜡包埋的小鼠棕色脂肪使用ATGL Antibody进行免疫组织化学分析，其中左图对照肽，右图抗原特异肽。 | |
Western blot analysis of extracts from NIH/3T3 and differentiated NIH/3T3-L1 cells, using ATGL antibody. 对NIH/3T3和分化的3T3-L1细胞抽提液使用ATGL antibody进行Western blot分析。 | |
