Arf6 Antibody
货号：
3546S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 3546S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Arf6 Antibody detects endogenous levels of total Arf6 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | ADP-ribosylation factor (Arf) proteins are low molecular weight GTP binding proteins that belong to the Ras GTPase superfamily (1). Arf proteins are grouped into three distinct classes based on amino acid sequence and structural similarity, with Arf6 as the single class III protein to date. Arf6 is localized mainly to the plasma membrane and endosomes (1,2). This small GTPase interacts with PIP5K, PLD and Rac1, proteins important in lipid metabolism and actin regulation. Arf6 function depends upon its cycling between GDP- and GTP-bound states, which is regulated by associated GAP and GEF factors (3,4). Plasma membrane-associated Arf6 appears to play several functions during the many steps of membrane trafficking, including regulating membrane receptor internalization in both clathrin-dependent and independent pathways, endosomal recycling, and proximal actin reorganization and remodeling (5,6). |
| 存放说明 | -20C |
| 计算分子量 | 19 |
参考图片Western blot analysis of extracts from various cell lines using Arf6 Antibody. 对多个细胞系提取物使用Arf6 Antibody进行Western blot分析。 |
