Angiopoietin-2 Antibody
货号:
2948S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 2948S |
反应种属 | Mouse |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | Angiopoietin-2 Antibody detects transfected levels of mouse angiopoietin-2 protein. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | Angiopoietins are a family of Tie receptor ligands. There are four angiopoietins discovered so far: angiopoietins 1, 2, 3 and 4 (Ang1, 2, 3, and 4) (1-3). Ang1 binds to the Tie-2 receptor and leads to its autophosphorylation and subsequent activation of downstream signaling pathways. It plays an important role in blood vessel formation, maturation and subsequent stabilization (1,4,5). Ang2 is an endothelium-specific growth factor that functions as an antagonist to Ang1, promotes vascular associated proinflammatory function, destabilizes quiescent endothelium, leads to vascular leakage and vascular destablization and remodeling (2,6,7). Ang2 is selectively expressed in many tumor tissues where, combined with other growth factors such as VEGF, it can promote vascular remodeling, angiogenesis and inflammation (7-9). |
存放说明 | -20C |
计算分子量 | 66 |
参考图片Western blot analysis of extracts from COS cells, untransfected or transfected with mouse angiopoietin-2, using Angiopoietin-2 Antibody.使用Angiopoietin-2对未转染或转染小鼠angiopoietin-2的COS细胞提取物进行western blot。 |