AML1 Antibody (Mouse Preferred)
货号：
8229S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 8229S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | AML1 Antibody (Mouse Preferred) detects endogenous levels of total AML1 protein. This antibody will recognize human AML1, however, we recommend AML1 (D33G6) XP® Rabbit mAb #4336 for detection of human AML1. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | AML1 (also known as Runx1, CBFA2, and PEBP2αB) is a member of the core binding factor (CBF) family of transcription factors (1,2). It is required for normal development of all hematopoietic lineages (3-5). AML1 forms a heterodimeric DNA binding complex with its partner protein CBFβ and regulates the expression of cellular genes by binding to promoter and enhancer elements. AML1 is commonly translocated in hematopoietic cancers: chromosomal translocations include t(8;21) AML1-ETO, t(12;21) TEL-AML and t(8;21) AML-M2 (6). Phosphorylation of AML1 on several potential serine and threonine sites, including Ser249, is thought to occur in an Erk-dependent manner (7,8). |
| 存放说明 | -20C |
| 计算分子量 | 55 |
参考图片Western blot analysis of extracts from various cell lines using AML1 Antibody (Mouse Preferred).Western免疫印迹。用 AML1 Antibody (Mouse Preferred)研究各种细胞系的细胞提取液。 |
