5-HTR1A Antibody
货号:
9879S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 9879S |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | Serotonin Receptor 1A/5-HTR1A Antibody recognizes transfected levels of total Serotonin Receptor 1A/5-HTR1A protein. Thus far, endogenous levels of Serotonin Receptor 1A have not been detected with this antibody. |
使用方法 | WB(1:1000) IP (1:50) |
性能供应商 | CST |
背景 | Serotonin (5-hydroxytryptamine/5-HT) is a monoamine found in the central nervous system. Serotonin receptors are mostly members of the G Protein-Coupled Receptor (GPCR) superfamily. GPCRs are a family of cell surface receptors containing seven transmembrane proteins. GPCRs activate signal transduction pathways and cyclic AMP formation (1). Seven subclasses of serotonin receptors (5-HTR) have been described (5-HTR1-7). There are five subclasses of 5-HTR1 (1A, 1B, 1D, 1E, and 1F). 5-HTR1A is an inhibitory GPCR expressed both in serotonergic neurons and in target areas receiving serotonergic innervation. These receptors are associated with depression, anxiety, and the response to antidepressants (2). |
存放说明 | -20C |
计算分子量 | 80-240 |
参考图片Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with human Serotonin Receptor 1A/5-HTR1A (+), using Serotonin Receptor 1A/5-HTR1A Antibody. |