MMP-2 Antibody
货号：
4022S 基本售价：
3250.0 元 规格：
-
产品信息
概述| 货号 | 4022S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | MMP-2 Antibody detects full length (proenzyme, 72 kDa) and cleaved (active enzyme, 64 kDa) MMP-2. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | The matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors and adhesion molecules (1). Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis (2-4). MMP activity correlates with cancer development (2). One mechanism of MMP regulation is transcriptional (5). Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein (5). |
| 存放说明 | -20C |
| 计算分子量 | 64, 72 |
参考图片Western blot analysis of partially purified, concentrated, serum-free medium containing human MMP-2, using MMP-2 Antibody.对含有人MMP-2的无血清培养基经过部分纯化，浓缩后使用MMP-2使用western blot分析。 |
