SOCS3 (L210) Antibody
货号：
2932T 基本售价：
1350.0 元 规格：
-
产品信息
概述| 货号 | 2932T |
| 反应种属 | Human,Mouse,Rat, |
| 来源宿主 | Rabbit |
| 应用 | WB |
| 目标/特异性 | SOCS3 (L210) Antibody detects endogenous levels of total SOCS3 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | The SOCS (suppressor of cytokine signaling) family members are negative regulators of cytokine signal transduction that inhibit the Jak/Stat pathway (1-3). The SOCS family consists of at least 8 members including the originally identified protein CIS1 (cytokine-inducible SH2-containing protein) as well as SOCS1 through SOCS7. Each SOCS family member contains a central SH2 domain and a conserved carboxy-terminal motif designated as the SOCS box. These proteins are important regulators of cytokine signaling, proliferation, differentiation and immune responses. |
| 存放说明 | -20C |
| 计算分子量 | 26 |
| 参考文献 | 1 . Alexander, W.S. et al. (1999) J Leukoc Biol 66, 588-92.
2 . Chen, X.P. et al. (2000) Immunity 13, 287-90.
3 . Hilton, D.J. et al. (1998) Proc Natl Acad Sci USA 95, 114-9.
4 . Bjørbaek, C. et al. (1998) Mol Cell 1, 619-25.
5 . Adams, T.E. et al. (1998) J Biol Chem 273, 1285-7.
6 . Soriano, S.F. et al. (2002) J Exp Med 196, 311-21.
7 . Emanuelli, B. et al. (2000) J Biol Chem 275, 15985-91.
8 . Stoiber, D. et al. (1999) J Immunol 163, 2640-7.
9 . Stoiber, D. et al. (2001) J Immunol 166, 466-72.
10 . Starr, R. et al. (1997) Nature 387, 917-21.
11 . Roberts, A.W. et al. (2001) Proc Natl Acad Sci USA 98, 9324-9.
12 . Seki, Y. et al. (2003) Nat Med 9, 1047-54.
13 . Shouda, T. et al. (2001) J Clin Invest 108, 1781-8.
14 . Fang, M. et al. (2005) Cell Mol Immunol 2, 373-7.
15 . Goren, I. et al. (2006) J Invest Dermatol 126, 477-85.
16 . Mori, H. et al. (2004) Nat Med 10, 739-43.
17 . Howard, J.K. et al. (2004) Nat Med 10, 734-8.
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参考图片Western blot analysis of extracts from various cell types using SOCS3 (L210) Antibody (left) and SOCS3 Antibody #2923 (right).Western免疫印迹。用SOCS3 (L210) Antibody (左图) 和SOCS3 Antibody #2923 (右图)研究各种细胞的细胞提取液。 |
