货号 | 4272T |
反应种属 | Human,Mouse,Rat,Monkey,D. melanogaster, |
来源宿主 | Rabbit |
应用 | WB, IHC-P |
目标/特异性 | Cytochrome c Antibody detects endogenous levels of cytochrome c protein. |
使用方法 | WB(1:1000) IHC-P (1:200) |
供应商 | CST |
灵敏度 | Endogenous |
背景 | Cytochrome c is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space (1). Upon apoptotic stimulation, cytochrome c released from mitochondria associates with procaspase-9 (47 kDa)/Apaf 1. This complex processes caspase-9 from inactive proenzyme to its active form (2). This event further triggers caspase-3 activation and eventually leads to apoptosis (3). |
存放说明 | -20C |
计算分子量 | 14 |
参考文献 | 1 . Schagger H.H. et al. (2002) Biochem. Biophys. Acta. 1555, 154-159. 2 . Li, P. et al. (1997) Cell 91, 479-489. 3 . Liu, X. et al. (1996) Cell 86, 147-157. |
Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using Cytochrome c Antibody. 免疫组织化学染色分析石蜡包埋人结肠癌组织。所用抗体为Cytochrome c Antibody。 | |
Immunohistochemical analysis of paraffin-embedded human prostate carcinoma, using Cytochrome c Antibody. 免疫组织化学染色分析石蜡包埋人前列腺癌组织。所用抗体为Cytochrome c Antibody。 | |
Western analysis of cell extracts from human (HeLa and Jurkat), monkey (COS), mouse (L929), rat (C6) and purified bovine cytochrome c, using Cytochrome c Antibody. Western blot分析人源(HeLa 和Jurkat)、猴子源(COS)、小鼠源 (L929)和大鼠源(C6) 细胞的细胞提取液和纯化的牛细胞色素C,所用抗体为 Cytochrome c Antibody。 |