SOCS2 Antibody
货号:
2779T 基本售价:
1350.0 元 规格:
-
产品信息
概述货号 | 2779T |
反应种属 | Human,Mouse,Rat, |
来源宿主 | Rabbit |
应用 | WB, IP |
目标/特异性 | SOCS2 Antibody detects endogenous levels of SOCS2 protein. |
使用方法 | WB(1:1000) IP (1:100) |
性能供应商 | CST |
灵敏度 | Endogenous |
背景 | The SOCS (suppressor of cytokine signaling) family members are negative regulators of cytokine signal transduction that inhibit the Jak/Stat pathway (1-3). The SOCS family consists of at least 8 members including the originally identified protein CIS1 (cytokine-inducible SH2-containing protein) as well as SOCS1 through SOCS7. Each SOCS family member contains a central SH2 domain and a conserved carboxy-terminal motif designated as the SOCS box. These proteins are important regulators of cytokine signaling, proliferation, differentiation and immune responses. |
存放说明 | -20C |
计算分子量 | 22 |
参考文献 | 1 . Alexander, W.S. et al. (1999) J Leukoc Biol 66, 588-92. 2 . Chen, X.P. et al. (2000) Immunity 13, 287-90. 3 . Hilton, D.J. et al. (1998) Proc Natl Acad Sci USA 95, 114-9. 4 . Rico-Bautista, E. et al. (2006) Cytokine Growth Factor Rev 17, 431-9. 5 . Favre, H. et al. (1999) FEBS Lett 453, 63-6. 6 . Metcalf, D. et al. (2000) Nature 405, 1069-73. 7 . Greenhalgh, C.J. et al. (2002) J Biol Chem 277, 40181-4. 8 . Greenhalgh, C.J. et al. (2005) J Clin Invest 115, 397-406. 9 . Starr, R. et al. (1997) Nature 387, 917-21. 10 . Tannahill, G.M. et al. (2005) Mol Cell Biol 25, 9115-26. 11 . Bullock, A.N. et al. (2006) Proc Natl Acad Sci U S A 103, 7637-42. 12 . Piessevaux, J. et al. (2006) J Biol Chem 281, 32953-66. 13 . Dey, B.R. et al. (1998) J Biol Chem 273, 24095-101.
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参考图片Western blot analysis of extracts from K562, A204 and PC12 cells using SOCS2 Antibody.Western免疫印迹。用SOCS2 Antibody研究K562, A204 和 PC12细胞的细胞提取液。 |