概述货号 | MAB3367-SP |
别名 | protein Wnt-8b; wingless-type MMTV integration site family, member 8B |
全称 | Wingless-type MMTV Integration Site Family, Member 8b | 反应种属 | Human/Mouse |
应用 | Immunohistochemistry(8-25 µg/mL)
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目标/特异性 | Detects mouse Wnt-8b in direct ELISAs. In direct ELISAs, no cross‑reactivity with recombinant mouse Wnt-1, -2b, -3a, -4, -5a, -5b, -8a, -9b, -10b, recombinant human Wnt-2, -7a, -7b, or -9a is observed. Immunohistochemical staining of the human neural cell line, NTera2, demonstrates that this antibody also recognizes human Wnt-8b. |
使用方法 | Immunohistochemistry: 8-25 µg/mL
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来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 | |
性能供应商 | R&D Systems |
Entrez Gene IDs | 7479 (Human); 22423 (Mouse); 293990 (Rat) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | E. coli-derived recombinant mouse Wnt‑8b |
生物活性 | Human, Mouse |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | Mouse Wnt-8b is a 40-50 kDa secreted glycoprotein member of the Wnt family of proteins. Mature mouse Wnt-8b is 329 aa in length and contains 24 cysteines plus three potential N-linked glycosylation sites. Little is known about Wnt-8b. It appears to play a role in forebrain development. The mature mouse protein is 100%, 98%, and 97% identical to mature rat, canine, and human Wnt-8b, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 | - A Leader in the Development of Reagents for Wnt Research
- Wnt Ligands (Wnts)
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