货号 | MAB2827-SP |
别名 | 2310008D05Rik; endothelial cell adhesion molecule; endothelial cell-selective adhesion molecule; HUEL (C4orf1)-interacting protein; LP4791 protein; W117m | 全称 | Endothelial Cell Adhesion Molecule |
反应种属 | Mouse |
应用 | Western Blot(1 µg/mL) |
目标/特异性 | Detects mouse ESAM in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human ESAM is observed. |
使用方法 | Western Blot: 1 µg/mL |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 90952 (Human); 69524 (Mouse) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse ESAM Gln30-Ser248 (predicted) Accession # Q925F2 |
生物活性 | Mouse |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | ESAM is a 55 kDa type I transmembrane glycoprotein belonging to the CTX (cortical thymocyte marker in Xenopus) family of cell adhesion molecules within the immunoglobulin superfamily. Other family members are CXADR, CLMP, JAM-A-C, CD2, A33, and BT-IgSF. The extracellular region of ESAM contains one V-type and one C2-type Ig domain and is involved in homophilic adhesion. Mouse ESAM extracellular domain shares 69% amino acid sequence identity with the corresponding region of human ESAM. ESAM is expressed on endothelial cells, activated platelets and megakaryocytes and can be found associated with cell-to-cell junctions. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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