货号 | MAB2776-SP |
别名 | NgR2; NgRH1; reticulon 4 receptor-like 2; RTN4RL2 | 全称 | Nogo-66 Receptor-related Protein 2/Nogo-66 Receptor Homolog 1/Reticulon-4 Receptor-like 2 |
反应种属 | Human |
应用 | Western Blot(1 µg/mL) |
目标/特异性 | Detects human NgR2/NgRH1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human (rh) NgR3 or rhNgR is observed. |
使用方法 | Western Blot: 1 µg/mL |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 349667 (Human) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human NgR2/NgRH1 Ala28-Leu401 Accession # Q86UN3 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | NgR2, also known as reticulon 4 receptor-like 2 and NgRH1, is a 60 kDaglycosylphosphatidylinositol-anchored protein that is expressedprimarily in the brain. It contains eight leucine-rich repeats that areflanked by cysteine-rich sequences at both the N- as well as theC-terminus. Membrane-anchored NgR2 can be solubilized through theaction of phospholipase or an unidentified MT-MMP to generate a 46 kDasoluble receptor. Mature human NgR2 shares 48% aa sequence identitywith human NgR3. It also shares 96% aa sequence identity with mouse andrat mature NgR2. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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