| 货号 | MAB3724-SP |
| 别名 | CARCAR1; Constitutive activator of retinoid response; constitutive active receptor; Constitutive active response; Constitutive androstane receptor; MB67; MGC150433; MGC97144; MGC97209; NR1I3; nuclear receptor subfamily 1 group I member 3; nuclear receptor subfamily 1, group I, member 3; orphan nuclear hormone receptor; Orphan nuclear receptor MB67 | 全称 | Constitutive Androstane Receptor |
| 反应种属 | Human/Mouse |
| 应用 | Western Blot(1 µg/mL) |
| 目标/特异性 | Detects mouse CAR/NR1I3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross-reactivity with recombinant human CAR is observed. |
| 使用方法 | Western Blot: 1 µg/mL |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 9970 (Human) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Expression of coxsackie and adenovirus receptor reduces the lung metastatic potential of murine tumor cells. | |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse CAR/NR1I3 Leu20-Gly237 Accession # P97792 |
| 生物活性 | Human, Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | CAR, (MB67; NR1I3) is a 40 kDa member of the NR1 subfamily of the nuclear hormone receptor family. It is predominantly expressed in the liver and forms a heterodimer with RXR. The heterodimer activates retinoic acid, xenobiotic and phenobarbital response elements. There are two isoforms. Each contains a DNA-binding hinge and dimerization domain. One is full-length at 352 amino acids while the other shows a 4 amino acid truncation at the extreme C-terminus. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
|