货号 | MAB3068-SP |
别名 | IL-1 R9; IL-1R-9; IL1R9IL-1 receptor accessory protein-like 2; IL-1R9IL-1RAPL-2; IL-1-RAPL-2; IL1RAPL-2IL1RAPL-2-related protein; interleukin 1 receptor 9; interleukin 1 receptor accessory protein-like 2; Three immunoglobulin domain-containing IL-1 receptor-related 1; TIGIRR-1; TIGIRR-1Interleukin-1 receptor 9; X-linked interleukin-1 receptor accessory protein-like 2 | 全称 | Interleukin 1 Receptor Accessory Protein-like 1 |
反应种属 | Mouse |
应用 | Western Blot(1 µg/mL) |
目标/特异性 | Detects mouse IL‑1 RAPL2/IL‑1 R9 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25% cross‑reactivity with recombinant human (rh) IL-1 RAPL2 is observed and no cross-reactivity with recombinant mouse (rm) IL-1 R1, rmIL-1 R2, rmIL-1 R4, rmIL-1 Rrp2, rmSIGIRR, rhIL-1 R3, rhIL-1 R4, rhIL-1 Rrp2, or rhIL-1 RAPL1 is observed. |
使用方法 | Western Blot: 1 µg/mL |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 26280 (Human); 60367 (Mouse) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse IL-1 RAPL2/IL‑1 R9 Asn18-Ala358 Accession # Q9ERS6 |
生物活性 | Mouse |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | Interleukin 1 receptor accessory protein-like 2 (IL-1 RAPL2), also known as TIGIRR-1 and IL-1 R9, is a member of the IL-1 RI-like family of the IL-1 R/Toll-like receptor superfamily. IL-1 RAPL2 is a type I transmembrane protein that contains three Ig-like domains in its extracellular region and one intracellular TIR domain. IL‑1 RAPL2 is expressed in the central nervous system, and its deletion is associated with some forms of X-linked mental retardation. An alternately spliced variant lacks the transmembrane and cytoplasmic regions. Within their extracellular domains, mouse IL-1 RAPL2 shares 99% amino acid sequence identity with human IL‑1 RAPL2. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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