货号 | MAB2920-SP |
别名 | DKFZp547J144; NgR3; NgRH2; NGRL2; nogo receptor-like 2; Nogo-66 receptor homolog 2; Nogo-66 receptor-related protein 3; reticulon 4 receptor-like 1; reticulon-4 receptor-like 1; RTN4RL1 | 全称 | Nogo-66 Receptor-related Protein 3/Nogo-66 Receptor Homolog 2/Reticulon-4 Receptor-like 1 |
反应种属 | Human |
应用 | Western Blot(1 µg/mL) |
目标/特异性 | Detects human NgR3/NgRH2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human NgRH1 is observed. |
使用方法 | Western Blot: 1 µg/mL |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 146760 (Human); 237847 (Mouse) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human NgR3/NgRH2 Cys25-Ala419 Accession # Q86UN2 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | NgR3, a Nogo-66 receptor homolog alternately known as reticulon 4receptor-like 1, Nogo receptor homolog 2 (NgRH2), or NgR3, is anapproximately 60 kDa glycosylphosphatidylinositol-anchoredglycoprotein expressed primarily in the brain. It contains eightleucine-rich repeats (LRR) flanked by conserved cysteines. Although LRRare typically involved in protein-protein interactions, NgR3 has notbeen shown to bind known Nogo-66 receptor ligands. Mature human NgR3shares 88%, 88%, 48% and 44% amino acid identity with mature mouseNgR3, rat NgR3, human NgRH1 and human NgR, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
|