货号 | MAB2427-SP |
别名 | FIL1- theta; FKSG75; IL1F10; IL-1HY2; interleukin 1 family, member 10 (theta); UNQ6119/PRO20041 | 全称 | Interleukin 1 Family Member 10 |
反应种属 | Human |
应用 | Western Blot(1 µg/mL) |
目标/特异性 | Detects human IL‑38/IL‑1F10 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant mouse IL-1F10 is observed and no cross-reactivity with recombinant human (rh) IL-1 alpha /IL-1F1 rhIL-1 beta /IL-1F2, rhIL-1ra/IL-1F3, rhIL-18/IL-1F4, rhIL-36Ra/IL‑1F5, rhIL-36 alpha /IL‑1F6, rhIL‑1F7/FIL1 zeta, rhIL-36 beta /IL-1F8, or rhIL-36 gamma /IL‑1F9 is observed. |
使用方法 | Western Blot: 1 µg/mL |
来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 84639 (Human); 215274 (Mouse) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | E. coli-derived recombinant human IL‑38/IL‑1F10 Met1-Trp152 Accession # Q8WWZ1 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
背景 | Human IL-38, previously called IL-1F10 or IL-1HY2, is a secreted cytokine belonging to the IL-1family. It is synthesized as a 152 amino acid mature protein that lacksan identifiable signal sequence. It binds to soluble IL-1 RI. HumanIL-38/IL-1F10 shares 82% aa sequence identity with mouse IL-38/IL-1F10. Human IL-38/IL-1F10 also shares 39% and 27% aa sequence identity with IL-1ra/IL-1F3 andIL-1 beta /IL-1F2, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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